HOME
Welcome To The Hockemeyer Lab
The focus of our work is to establish reliable models of human diseases using genetically engineered human and stem cell and mouse models and functional genomics screening approaches. We are particularly interested in developing rigorous genetic approaches to study human disease, development and cell biology where conventional animal models or tissue culture systems do not adequately recapitulate human biology. To do this we are leveraging our expertise in human stem cell techniques and genome editing, humanized mouse models to elucidate processes of human stem cells renewal and differentiation and during tumor formation.
Recent Publications
2024 - 2025
Li TL, Blair JD, Yoo T, Grant GA, Hockemeyer D, Porter BE, Bateup HS.
mTORC1 activation drives astrocyte reactivity in cortical tubers and brain organoid models of TSC
bioRxiv
2025 Mar 18.
doi: 10.1101/2025.02.28.640914. PubMed PMID: 40093155.
Martin A, Schabort J, Bartke-Croughan R, Tran S, Preetham A, Lu R, Ho R, Gao J, Jenkins S, Boyle J, Ghanim GE, Jagota M, Song YS, Li H, Hockemeyer D.
Active telomere elongation by a subclass of cancer-associated POT1 mutations
Genes Dev.
2025 Feb 27.
doi: 10.1111/bjh.19851. Epub 2024 Oct 27. PubMed PMID: 40015989.
Savage SA, Bertuch AA.
Different phenotypes with different endings-Telomere biology disorders and cancer predisposition with long telomeres.
Br J Haematol.
2024 Oct 27.
doi: 10.1111/bjh.19851. [Epub ahead of print] Review. PubMed PMID: 39462986.
Recent News
2023 Hockemeyer Holiday Party
12/2023
2022 Hockemeyer Holiday Party
12/2022
2022 Hockemeyer Halloween Party
10/2022
